Flybrain / Murmur: data in this folder ======================================== connectome..part1.bin, part2.bin, part3.bin circuit..json These files are derived from the FlyWire whole-brain connectome of an adult female Drosophila melanogaster (FAFB), public release v630, by the FlyWire Consortium, as prepared by Shiu et al. (2024) in Drosophila_brain_model (https://github.com/philshiu/Drosophila_brain_model): the signed connectivity table (2023_03_23_connectivity_630_final.parquet) and the neuron ID list (2023_03_23_completeness_630_final.csv). Licence ------- The FlyWire connectome data is licensed under the Creative Commons Attribution-NonCommercial 4.0 International licence (CC BY-NC 4.0): https://creativecommons.org/licenses/by-nc/4.0/ These derived files are shared under the same licence, for non-commercial use, with the attribution below. The Drosophila_brain_model code is MIT-licensed. Changes made (the files are modified) ------------------------------------- - Neurons renumbered (reverse Cuthill-McKee order) and the connectivity stored as a compressed sparse row graph: per-neuron degrees, delta-encoded targets, and the signed synapse counts (one byte each, with an escape list for larger ones). A key restores the original neuron order, and the 64-bit FlyWire root IDs are included. - A fixed permutation of destinations (seed 8128) is included for the instrument's "rewired" control. - Compressed with gzip and split into parts for delivery. - circuit..json is a small display subset: the 21 sugar-sensing inputs, MN9 and selected interneurons with their strongest links. No connection was added, removed or re-weighted. Attribution ----------- FlyWire whole-brain connectome (FAFB), public release v630, FlyWire Consortium. Model and data preparation after Shiu, P.K. et al. A Drosophila computational brain model reveals sensorimotor processing. Nature 634, 210-219 (2024). https://doi.org/10.1038/s41586-024-07763-9 Please also cite: - Dorkenwald, S. et al. Neuronal wiring diagram of an adult brain. Nature 634, 124-138 (2024). https://doi.org/10.1038/s41586-024-07558-y - Schlegel, P. et al. Whole-brain annotation and multi-connectome cell typing of Drosophila. Nature 634, 139-152 (2024). https://doi.org/10.1038/s41586-024-07686-5 - Eckstein, N., Bates, A.S. et al. Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster. Cell 187, 2574-2594 (2024). https://doi.org/10.1016/j.cell.2024.03.016 FlyWire: https://flywire.ai